Pug Dog Encephalitis

PDE is an inflammatory brain disease that is usually progressive and fatal. Signs of PDE can include seizure, not walking correctly and blindness. The disease is believed to be an autosomal-recessive condition. This means that dogs that inherit two copies of a PDE gene mutation (one from its mother and one from its father) will have an increased risk of developing the condition. This disease is not fully understood and it is believed that environmental factors or other genetic influences can also contribute to whether a dog becomes affected. Current research suggests that 12.5% of dogs that have two copies of the PDE gene variant will develop PDE.

There is a DNA test available to check the risk of developing PDE, there is a list of laboratories offering the test on the Kennel Club website – click here

Information copied from the Kennel Club website (accurate as of 26/02/2023)